The Key to Program Management in Today’s Enterprise :old-key: Many people interchange “program management” with “project management,” assuming, perhaps, that their meanings are basically the same. While the two terms are interrelated, they are vastly different in how they are approached and by whom. The enterprise program management office (EPMO) often leads program management for outcomes aligned with achieving corporate objectives. One of its primary charters is to orchestrate coordination and interdependencies of cross-enterprise projects comprising the program that together realize strategic goals.